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Zymeworks was a private biopharmaceutical company based in Vancouver, Canada. The company leveraged its novel platforms to design and develop best-in-class bi-specific antibody and ADC treatments. Its lead program, zanidatamab, a bispecific antibody targeting HER2-expressing cancers. In 2017, Zymeworks went public on the NYSE under the ticker ZYME.

Specialty

Solid tumors

Fund name

CTI LSF I

Position

Lead

Board

Director

Investment Date

January 22, 2009

Exit Detail

IPO on the NYSE

Initial Series Round

Series A

Investment Thesis

Zymeworks had two innovative rationale design platforms – Azymetric and Zymelink, for rationale design of antibody-based treatments

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March 22, 2016

Zymeworks Completes Acquisition of Kairos Therapeutics Creating a Leader in Biologics Drug Discovery and Development

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June 23, 2009

Zymeworks Closes C$3.4M Financing Round and Announces Changes to its Board of Directors

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April 26, 2016

Zymeworks Names Diana Hausman, M.D. Chief Medical Officer

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April 26, 2016

Zymeworks and GSK Enter Second Strategic Collaboration to Develop and Commercialize Bi-Specific Antibodies

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August 29, 2011

Zymeworks Snags $187M Deal With Merck to Discover Multi-Pronged Antibodies

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December 5, 2017

Zymeworks Presents Results of the Completed Dose Escalation Portion of the Ongoing Phase 1 Study of ZW25 at the San Antonio Breast Cancer Symposium

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November 27, 2017

Zymeworks Announces License Agreement with Johnson & Johnson Innovation to Develop and Commercialize Next Generation Bispecific Antibody Therapeutics

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April 27, 2017

Zymeworks Announces Pricing of Initial Public Offering

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January 8, 2016

Zymeworks Announces $61.5 Million Financing to Support the Clinical Development of its Pipeline of Azymetric™ Antibody Therapeutics

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June 29, 2010

Zymeworks Closes C$3.2M Round of Financing

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September 4, 2018

Zymeworks Reports IND-Submission Milestone Achieved in Lilly Collaboration

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